The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2017

Filed:

Feb. 27, 2014
Applicant:

Fundación Para LA Investigación Médica Aplicada, Pamplona, ES;

Inventors:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/90 (2006.01); A61K 31/519 (2006.01); C07D 487/00 (2006.01); C07D 487/04 (2006.01); C07D 401/14 (2006.01); C07D 213/81 (2006.01); C07D 401/12 (2006.01); C07D 471/04 (2006.01); C07D 487/14 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/519 (2013.01); C07D 213/81 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 471/04 (2013.01); C07D 487/14 (2013.01);
Abstract

It relates to certain compounds having a polycyclic structure and a hydroxamic acid moiety, wherein the polycyclic structure comprises at least three ring systems, wherein one ring system is a polycyclic ring system comprising from 2 to 4 rings; at least one ring is an aromatic ring; and wherein the structure comprises at least 3 nitrogen atoms and 1 oxygen atom. It also relates to a process for their preparation, as well as to pharmaceutical compositions containing them, and to their use in medicine, in particular in the treatment and/or prevention of neurological disorders coursing with a cognition deficit or impairment, or neurodegenerative diseases. wherein Bis a radical selected from the group consisting of formula (A″), formula (B″), formula (C″), and formula (D″):


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