The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 21, 2017
Filed:
Sep. 18, 2008
Applicants:
Virginie Sophie Poncelet, Le Manoir sur Seine, FR;
Sophie Coupa, Belbeuf, FR;
Pierre-henri Storck, Ramsgate, GB;
Bruno Schoentjes, Bois-Gullaume, FR;
Inventors:
Virginie Sophie Poncelet, Le Manoir sur Seine, FR;
Sophie Coupa, Belbeuf, FR;
Pierre-Henri Storck, Ramsgate, GB;
Bruno Schoentjes, Bois-Gullaume, FR;
Assignee:
Janssen Pharmaceutica NV, Beerse, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 59/13 (2006.01); C07D 311/04 (2006.01); A61K 31/352 (2006.01); C07D 491/052 (2006.01); A61K 31/4741 (2006.01); C07D 405/10 (2006.01); A61K 31/4184 (2006.01); A61K 31/192 (2006.01); C07D 405/04 (2006.01); A61K 31/4709 (2006.01); C07D 409/10 (2006.01); A61K 31/381 (2006.01); A61K 45/06 (2006.01); C07D 401/12 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); C07D 487/04 (2013.01);
Abstract
The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds: wherein n, m, p, s, t, R, R, R, R, R, R, R, R, X, Y, Q and Z have defined meanings.