The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2017

Filed:

Sep. 14, 2010
Applicants:

David Simpson, Mechanicsville, VA (US);

Gary Bowlin, Mechanicsville, VA (US);

Raymond Colello, Chester, VA (US);

Woon Chow, Glen Allen, VA (US);

Balendu Shekhar Jha, Richmond, VA (US);

Inventors:

David Simpson, Mechanicsville, VA (US);

Gary Bowlin, Mechanicsville, VA (US);

Raymond Colello, Chester, VA (US);

Woon Chow, Glen Allen, VA (US);

Balendu Shekhar Jha, Richmond, VA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61L 27/18 (2006.01); A61F 2/02 (2006.01); A61B 17/11 (2006.01);
U.S. Cl.
CPC ...
A61L 27/18 (2013.01); A61B 17/1128 (2013.01); A61F 2/02 (2013.01); A61L 2430/32 (2013.01);
Abstract

Nerve guides which are formed from three dimensional (3D) arrays of highly aligned electrospun fibers are provided. The electrospun fibers are oriented parallel to the long axis of the guide, and gaps and elongated spaces between the stacked fiber arrays provide channels for directed axonal growth. In some embodiments, the nerve guides also comprise high precision gradients of beneficial substances such as growth factors, which aid in nerve regeneration and growth along the guide.


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