The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2017

Filed:

Jul. 17, 2015
Applicants:

Research Development Foundation, Carson City, NV (US);

Research Development Foundation, Carson City, NV (US);

Inventors:

Wylie W. Vale, Jr.;

Joan M. Vaughan, San Diego, CA (US);

Cindy Donaldson, San Diego, CA (US);

Wolfgang Fischer, Encinitas, CA (US);

Jean E. F. Rivier, La Jolla, CA (US);

Assignee:

Research Development Foundation, Carson City, NV (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); A61K 38/22 (2006.01); C07K 14/575 (2006.01);
U.S. Cl.
CPC ...
A61K 38/2228 (2013.01); C07K 14/4705 (2013.01); C07K 14/57509 (2013.01); Y10T 428/13 (2015.01);
Abstract

Disclosed are polypeptides that are analogs of urocortin 2 that have pharmacological activity similar to urocortin 2 but have improved water solubility compared to urocortin 2, and pharmaceutical compositions of the polypeptides of the present invention. Also disclosed are polynucleotides encoding the polypeptides, and methods of treating pathophysiological states employing pharmaceutical compositions of the polypeptides and polynucleotides of the present invention. In addition, disclosed are vectors and host cells that include a nucleic acid encoding a polypeptide of the present invention, and kits that include pharmaceutical compositions of the present invention.


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