The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2017

Filed:

Apr. 05, 2013
Applicant:

Allergan, Inc., Irvine, CA (US);

Inventors:

Patrick M. Hughes, Aliso Viejo, CA (US);

Orest Olejnik, Coto de Caza, CA (US);

Scott M. Whitcup, Laguna Hills, CA (US);

James A. Burke, Santa Ana, CA (US);

Assignee:

Allergan, Inc., Irvine, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 38/13 (2006.01); A61K 47/36 (2006.01); A61K 31/00 (2006.01); A61K 9/14 (2006.01); A61K 9/10 (2006.01);
U.S. Cl.
CPC ...
A61K 38/13 (2013.01); A61K 9/0048 (2013.01); A61K 9/0051 (2013.01); A61K 31/00 (2013.01); A61K 47/36 (2013.01); A61K 9/10 (2013.01); A61K 9/14 (2013.01); Y10S 514/912 (2013.01);
Abstract

Compositions, and methods of using such compositions, useful for injection into the posterior segments of human or animal eyes are provided. Such compositions include small particles of a poorly soluble therapeutic agent that facilitates formation of concentrated regions of the therapeutic agent in the retinal pigmented epithelium of an eye. The particles are formed by combining a therapeutic agent with an ophthalmically acceptable polymer component. The particles have sizes less than about 3000 nanometers, and in some cases, less than about 200 nanometers. One example of a composition includes particles of triamcinolone acetonide and hyaluronic acid have a size less than about 3000 nanometers.


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