The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2017

Filed:

Aug. 06, 2016
Applicants:

Yuhua LI, Landenberg, PA (US);

Benjamin Chien, Woodside, CA (US);

Inventors:

Yuhua Li, Landenberg, PA (US);

Benjamin Chien, Woodside, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/09 (2006.01); A61K 9/00 (2006.01); A61K 47/34 (2006.01); A61K 47/22 (2006.01);
U.S. Cl.
CPC ...
A61K 38/09 (2013.01); A61K 9/0024 (2013.01); A61K 47/22 (2013.01); A61K 47/34 (2013.01);
Abstract

The present invention provides for a stabilized biodegradable polymeric composition useful as a controlled release delivery system for peptide agents. The compositions of the present invention comprise a) a beneficial salt of a peptide agent formed with a strong acid that minimizes or prevents the interaction/reaction between the peptide agent and the polymer in an organic solution; b) a biodegradable polymer; c) a pharmaceutically acceptable organic solvent; and d) optionally one or more excipients. The present invention also relates to a method of manufacturing and a method of use thereof.


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