The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 21, 2017
Filed:
Oct. 05, 2015
Applicant:
Biogen MA Inc., Cambridge, MA (US);
Inventors:
Jermaine Thomas, Chelsea, MA (US);
Xiaogao Liu, Dover, MA (US);
Edward Yin-Shiang Lin, Ashland, MA (US);
Guo Zhu Zheng, Lexington, MA (US);
Bin Ma, Arlington, MA (US);
Richard D. Caldwell, Brookline, MA (US);
Kevin M. Guckian, Northborough, MA (US);
Gnanasambandam Kumaravel, Lexington, MA (US);
Arthur G. Taveras, Boston, MA (US);
Assignee:
BIOGEN MA INC., Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/695 (2006.01); A61K 31/11 (2006.01); A61K 31/18 (2006.01); A61K 31/216 (2006.01); A61K 31/197 (2006.01); A61K 31/397 (2006.01); A61K 31/40 (2006.01); A61K 31/445 (2006.01); A61K 31/683 (2006.01); A61K 31/662 (2006.01); A61K 31/47 (2006.01); A61K 31/277 (2006.01); A61K 31/41 (2006.01); A61K 31/4709 (2006.01); A61K 31/472 (2006.01); A61K 31/337 (2006.01); A61K 31/517 (2006.01); A61K 31/428 (2006.01); A61K 31/404 (2006.01); A61K 45/06 (2006.01); A61K 31/085 (2006.01); C07C 229/14 (2006.01); C07C 229/22 (2006.01); C07C 229/46 (2006.01); C07C 229/48 (2006.01); C07C 237/08 (2006.01); C07C 237/52 (2006.01); C07C 309/14 (2006.01); C07C 311/51 (2006.01); C07D 205/04 (2006.01); C07D 207/16 (2006.01); C07D 209/08 (2006.01); C07D 211/60 (2006.01); C07D 211/62 (2006.01); C07D 215/20 (2006.01); C07D 217/24 (2006.01); C07D 257/04 (2006.01); C07D 305/08 (2006.01); C07D 403/06 (2006.01); C07D 417/06 (2006.01); C07F 9/38 (2006.01); C07F 9/40 (2006.01); C07C 43/247 (2006.01); C07C 47/575 (2006.01); C07C 255/54 (2006.01); C07D 215/227 (2006.01); C07D 217/04 (2006.01); C07D 239/74 (2006.01); C07D 277/64 (2006.01); C07D 401/06 (2006.01); C07F 7/08 (2006.01);
U.S. Cl.
CPC ...
A61K 31/695 (2013.01); A61K 31/085 (2013.01); A61K 31/11 (2013.01); A61K 31/18 (2013.01); A61K 31/197 (2013.01); A61K 31/216 (2013.01); A61K 31/277 (2013.01); A61K 31/337 (2013.01); A61K 31/397 (2013.01); A61K 31/40 (2013.01); A61K 31/404 (2013.01); A61K 31/41 (2013.01); A61K 31/428 (2013.01); A61K 31/445 (2013.01); A61K 31/47 (2013.01); A61K 31/472 (2013.01); A61K 31/4709 (2013.01); A61K 31/517 (2013.01); A61K 31/662 (2013.01); A61K 31/683 (2013.01); A61K 45/06 (2013.01); C07C 43/247 (2013.01); C07C 47/575 (2013.01); C07C 229/14 (2013.01); C07C 229/22 (2013.01); C07C 229/46 (2013.01); C07C 229/48 (2013.01); C07C 237/08 (2013.01); C07C 237/52 (2013.01); C07C 255/54 (2013.01); C07C 309/14 (2013.01); C07C 311/51 (2013.01); C07D 205/04 (2013.01); C07D 207/16 (2013.01); C07D 209/08 (2013.01); C07D 211/60 (2013.01); C07D 211/62 (2013.01); C07D 215/20 (2013.01); C07D 215/227 (2013.01); C07D 217/04 (2013.01); C07D 217/24 (2013.01); C07D 239/74 (2013.01); C07D 257/04 (2013.01); C07D 277/64 (2013.01); C07D 305/08 (2013.01); C07D 401/06 (2013.01); C07D 403/06 (2013.01); C07D 417/06 (2013.01); C07F 7/081 (2013.01); C07F 9/3808 (2013.01); C07F 9/3834 (2013.01); C07F 9/4006 (2013.01); C07C 2101/02 (2013.01); C07C 2101/04 (2013.01); C07C 2101/08 (2013.01); C07C 2101/14 (2013.01); C07C 2101/16 (2013.01);
Abstract
Compounds that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphin-gosine analogs that, after phosphorylation, can behave as agonists at S1P receptors.