The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2017

Filed:

Aug. 10, 2012
Applicants:

Syed Hossainy, Hayward, CA (US);

Dariush Davalian, San Jose, CA (US);

Mikael Trollsas, San Jose, CA (US);

John Stankus, Campbell, CA (US);

Jinping Wan, Sunnyvale, CA (US);

Inventors:

Syed Hossainy, Hayward, CA (US);

Dariush Davalian, San Jose, CA (US);

Mikael Trollsas, San Jose, CA (US);

John Stankus, Campbell, CA (US);

Yuet Mei Khong, Sunnyvale, CA (US);

Jinping Wan, Sunnyvale, CA (US);

Assignee:

Abbott Cardiovascular Systems Inc., Santa Clara, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 37/00 (2006.01); A61K 31/409 (2006.01); A61K 9/00 (2006.01); A61K 9/127 (2006.01); A61K 9/51 (2006.01); A61L 29/16 (2006.01); A61K 41/00 (2006.01); A61M 25/00 (2006.01); A61M 25/10 (2013.01);
U.S. Cl.
CPC ...
A61K 31/409 (2013.01); A61K 9/0009 (2013.01); A61K 9/0019 (2013.01); A61K 9/1272 (2013.01); A61K 9/5146 (2013.01); A61K 41/0071 (2013.01); A61L 29/16 (2013.01); A61L 2300/224 (2013.01); A61L 2300/626 (2013.01); A61M 25/0045 (2013.01); A61M 25/10 (2013.01); A61M 2025/105 (2013.01); A61M 2025/1086 (2013.01);
Abstract

This invention relates to photodynamic therapy (PDT) of vulnerable plaque using two pluralities of nanoparticles, one plurality comprising a PDT agent that is sensitive to blue-green light wherein the nanoparticles are capable of penetrating only into the fibrous cap of the vulnerable plaque and one plurality comprising a PDT agent that is sensitive to red light wherein the nanoparticles are capable of penetrating into the core of the vulnerable plaque.


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