The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2017

Filed:

Jan. 22, 2013
Applicant:

Echo Therapeutics, Inc., Franklin, MA (US);

Inventors:

Han Chuang, Canton, MA (US);

Juan P. Eslava, Boylston, MA (US);

James P. Hurley, Foxboro, MA (US);

Debashis Ghosh, Ashland, MA (US);

Keith Krystyniak, Chelmsford, MA (US);

Scott C. Kellogg, Mattapoisett, MA (US);

Assignee:

Echo Therapeutics, Inc., Iselin, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/05 (2006.01); A61B 5/00 (2006.01); A61B 5/053 (2006.01); A61B 17/54 (2006.01); A61B 18/20 (2006.01); A61N 1/04 (2006.01); A61N 1/32 (2006.01); A61B 17/00 (2006.01); A61B 17/32 (2006.01); A61B 18/00 (2006.01); A61M 37/00 (2006.01);
U.S. Cl.
CPC ...
A61B 5/442 (2013.01); A61B 5/0531 (2013.01); A61B 17/54 (2013.01); A61B 18/20 (2013.01); A61N 1/042 (2013.01); A61N 1/044 (2013.01); A61N 1/0424 (2013.01); A61N 1/0436 (2013.01); A61N 1/327 (2013.01); A61B 5/7239 (2013.01); A61B 18/203 (2013.01); A61B 2017/00761 (2013.01); A61B 2017/00765 (2013.01); A61B 2017/320004 (2013.01); A61B 2018/00452 (2013.01); A61B 2018/00642 (2013.01); A61M 2037/0007 (2013.01); A61N 1/328 (2013.01);
Abstract

Devices, systems, kits and methods for increasing the skin's permeability controlled by measured skin electrical parameter are described herein. They may be used for transdermal drug delivery and/or analyte extraction or measurement. The controlled abrasion device contains (i) a hand piece, (ii) an abrasive tip, (iii) a feedback control mechanism, (iv) two or more electrodes, and (v) an electrical motor. The feedback control mechanism may be an internal feedback control mechanism or an external feedback control. The kit contains the controlled abrasion-device, one or more abrasive tips, optionally with a wetting fluid. The method for increasing the skin's permeability requires applying the controlled abrasion device to a portion of the skin's surface for a short period of time, until the desired level of permeability is reached. Then the abrasion device is removed, and a drug delivery composition or device or an analyte sensor is applied to the treated site.


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