The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2017
Filed:
Oct. 03, 2014
Applicant:
Aptose Biosciences Inc., Toronto, Ontario, CA;
Inventor:
William G. Rice, Del Mar, CA (US);
Assignee:
Aptose Biosciences Inc., Toronto, Ontario, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); C12Q 1/68 (2006.01); C07D 471/14 (2006.01); A61K 31/4745 (2006.01); A61K 45/06 (2006.01); A61K 49/00 (2006.01); A61K 31/706 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); A61K 31/4745 (2013.01); A61K 31/706 (2013.01); A61K 45/06 (2013.01); A61K 49/0004 (2013.01); C07D 471/14 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01);
Abstract
The present invention relates to compositions and methods for treating of cancer. In some embodiments, the invention relates to the use of agents that can modulate a component in the CDX2-KLF4 signaling pathway to treat myelodysplastic syndromes (MDS), acute myelogenous leukemia (AML), acute lymphocytic leukemia (ALL), adult T-cell leukaemia (ATLL), lymphoma, gastric cancer, multiple myeloma, or combinations thereof, or a condition associated with abnormal activity of the CDX2-KLF4 signaling pathway.