The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 14, 2017

Filed:

Jun. 26, 2012
Applicants:

DE Yang, Frederick, MD (US);

Joost J. Oppenheim, Bethesda, MD (US);

Michael Bustin, Rockville, MD (US);

Inventors:

De Yang, Frederick, MD (US);

Joost J. Oppenheim, Bethesda, MD (US);

Michael Bustin, Rockville, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/19 (2006.01); C12N 5/0784 (2010.01); A61K 38/17 (2006.01); A61K 39/07 (2006.01); A61K 39/39 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0639 (2013.01); A61K 38/1709 (2013.01); A61K 39/07 (2013.01); A61K 39/39 (2013.01); A61K 2039/53 (2013.01); A61K 2039/55516 (2013.01); A61K 2039/57 (2013.01); C12N 2501/05 (2013.01); C12N 2501/23 (2013.01);
Abstract

A method of enhancing an antigen-specific immune response in a host comprising administering to the host an HMGN polypeptide comprising at least one of HMGN1, HMGN3a, HMGN3b, HMGN4, Nsbp1, or a functional fragment thereof, in an amount effective to enhance an antigen-specific immune response; as well as a pharmaceutical composition comprising an HMGN polypeptide comprising at least one of HMGN1, HMGN3a, HMGN3b, HMGN4, Nsbp1, or a functional fragment thereof, and an antigen, or nucleic acids encoding such molecules; and related methods and compositions.


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