The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2017
Filed:
Dec. 02, 2008
Subrata Sinha, New Delhi, IN;
Ashutosh Tiwari, New Delhi, IN;
Navin Khanna, New Delhi, IN;
Subrat K. Acharya, New Delhi, IN;
Subrata Sinha, New Delhi, IN;
Ashutosh Tiwari, New Delhi, IN;
Navin Khanna, New Delhi, IN;
Subrat K. Acharya, New Delhi, IN;
Department of Biotechnology, New Delhi, IN;
All India Institute of Medical Sciences, New Delhi, IN;
International Center for Genetic and Biotechnology, New Delhi, IN;
Abstract
This invention relates to a high affinity recombinant humanized antibody fragment (scFv) specific for hepatitis B surface antigen having unique inter/intra chain bonding interaction because of 28 altered amino acid residues from the original mouse (5S) antibody and its chimeric Fab form, wherein fine tuning of the vernier zone residue makes it closer to the human sequence without any structural constraints.