The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2017
Filed:
Mar. 01, 2013
Applicant:
Medimmune, Llc, Gaithersburg, MD (US);
Inventors:
Changshou Gao, Gaithersburg, MD (US);
Herren Wu, Gaithersburg, MD (US);
Assignee:
MedImmune, LLC, Gaithersburg, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/28 (2006.01); C07K 16/22 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C07K 16/00 (2013.01); C07K 16/22 (2013.01); C07K 16/2842 (2013.01); C07K 16/2848 (2013.01); C07K 16/2866 (2013.01); C07K 16/005 (2013.01); C07K 2317/21 (2013.01); C07K 2317/622 (2013.01); C07K 2317/71 (2013.01); C07K 2317/732 (2013.01); C07K 2317/734 (2013.01); C07K 2319/03 (2013.01); C07K 2319/035 (2013.01); C07K 2319/30 (2013.01); C12N 15/1037 (2013.01);
Abstract
The present invention relates to a viral vector encoding for a library of antibodies or antibody fragments that are displayed on the cell membrane when expressed in a cell. The present invention provides cells comprising the viral vector nucleic acids and methods of screening the libraries for antibodies or antibody fragments with desired characteristics.