The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2017
Filed:
Nov. 15, 2012
Applicant:
Trustees of Boston University, Boston, MA (US);
Inventors:
Scott E. Schaus, Boston, MA (US);
Lauren Brown, Brighton, MA (US);
John Connor, Newton, MA (US);
Ken William Dower, Medford, MA (US);
Assignee:
Trustees of Boston University, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); C07D 471/04 (2006.01); A61K 45/06 (2006.01); C12Q 1/70 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/519 (2013.01); A61K 45/06 (2013.01); C12Q 1/70 (2013.01);
Abstract
Provided herein are novel small molecule pyridomyrimidone viral inhibitor agents of Formula (I), such as 4-acetyl-2,3,7,8-tetrahydro-3-phenylpyrido[1,2-f]pyrimidin-1-one, and methods of using pharmaceutical or therapeutic compositions comprising such viral inhibitor agents of Formula (I) in inhibiting and treating viral infections including orthopox and retroviral infections. Methods of synthesizing such agents are also provided herein.