The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2017
Filed:
Nov. 01, 2013
Whitehead Institute for Biomedical Research, Cambridge, MA (US);
Dana-farber Cancer Institute, Inc., Boston, MA (US);
James E. Bradner, Weston, MA (US);
Michael R. McKeown, Brookline, MA (US);
Peter B. Rahl, Natick, MA (US);
Richard A. Young, Boston, MA (US);
Jason J. Marineau, Franklin, MA (US);
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Whitehead Institute for Biomedical Research, Cambridge, MA (US);
Abstract
The present invention provides compounds of Formula (I-A), (I-B), and (I-C), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting Myc (e.g., c-Myc) activity. The present invention further provides methods of using the compounds described herein for treating Myc-mediated disorders (e.g., cancer and other proliferative diseases). The present invention also provides assays for identifying Myc inhibitors.