The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 14, 2017

Filed:

Jun. 25, 2013
Applicant:

Sunshine Lake Pharma Co., Ltd., Dongguan, Guangdong, CN;

Inventors:

Zheng Gu, Dongguan, CN;

Guanpeng Qiu, Dongguan, CN;

Wuyong Wu, Dongguan, CN;

Panpan Kang, Dongguan, CN;

Zongyuan Zhang, Dongguan, CN;

Gang Chen, Dongguan, CN;

Chengsheng Lan, Dongguan, CN;

Yonggang Wei, Dongguan, CN;

Jiaping Wen, Dongguan, CN;

Guozhi Zhu, Dongguan, CN;

Yonghua Lu, Dongguan, CN;

Heran Wang, Dongguan, CN;

Yincai Wang, Dongguan, CN;

Mingyun Yuan, Dongguan, CN;

Kangzhi Ye, Dongguan, CN;

Guizhuan Su, Dongguan, CN;

PengCho Tang, Dongguan, CN;

Assignee:

SUNSHINE LAKE PHARMA CO., LTD., Dongguan, Guangdong, CN;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 207/16 (2006.01); A61K 31/40 (2006.01); C07D 405/12 (2006.01); C07D 209/52 (2006.01); A61K 31/403 (2006.01); C07C 217/52 (2006.01); A61K 45/06 (2006.01); C07C 255/47 (2006.01); C07C 213/02 (2006.01); C07C 253/30 (2006.01); C07C 249/08 (2006.01); A61K 31/4025 (2006.01);
U.S. Cl.
CPC ...
C07D 207/16 (2013.01); A61K 31/40 (2013.01); A61K 31/403 (2013.01); A61K 31/4025 (2013.01); A61K 45/06 (2013.01); C07C 213/02 (2013.01); C07C 217/52 (2013.01); C07C 249/08 (2013.01); C07C 253/30 (2013.01); C07C 255/47 (2013.01); C07D 209/52 (2013.01); C07D 405/12 (2013.01); C07C 2101/02 (2013.01); C07C 2102/22 (2013.01); C07C 2103/94 (2013.01);
Abstract

The invention relates to hexahydropentaleno derivatives, the preparation method and use in medicine thereof, and in particular to hexahydropentaleno derivatives or stereo-isomers or pharmaceutically acceptable salts thereof as shown in general formula (I), and to the preparation method therefor and pharmaceutical compositions comprising the derivatives, and to the use thereof as a therapeutical agent, especially as a DPP-IV inhibitor. The definition of each substituent in formula (I) is the same as the definition in the description.


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