The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2017
Filed:
Apr. 25, 2014
Applicant:
Emory University, Atlanta, GA (US);
Inventor:
Jack Arbiser, Atlanta, GA (US);
Assignee:
Emory University, Atlanta, GA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 251/30 (2006.01); A61K 31/15 (2006.01); A61K 45/06 (2006.01); C09B 11/12 (2006.01); C07C 251/22 (2006.01); C07D 223/28 (2006.01);
U.S. Cl.
CPC ...
C07C 251/30 (2013.01); A61K 31/15 (2013.01); A61K 45/06 (2013.01); C07C 251/22 (2013.01); C07D 223/28 (2013.01); C09B 11/12 (2013.01); C07C 2102/10 (2013.01);
Abstract
This disclosure relates to N-(4-(bis(4-(dimethylamino)phenyl)methylene)-8 -(dimethylamino)naphthalen-1(4H)-ylidene)-N-methylmethanaminium, derivatives, and uses related thereto. In certain embodiments, the disclosure relates to compounds of formula I. In certain embodiments, the disclosure relates to methods of treating or preventing Nox related diseases and conditions comprising administering an effective amount of compounds disclosed herein to a subject in need thereof. In certain embodiments, the Nox related disease or condition is cancer.