The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 14, 2017

Filed:

Feb. 05, 2014
Applicants:

B.g. Negev Technologies and Applications Ltd., Beer Sheva, IL;

Ramot AT Tel-aviv University Ltd., Tel Aviv, IL;

Inventors:

Joseph Kost, Omer, IL;

Riki Goldbart, Lehavim, IL;

Tamar Traitel, Beer Sheva, IL;

Eliz Lewis Amar, Beer Sheva, IL;

Rinat Lifshiz, Bnei Dror, IL;

Dan Peer, Kiryat Ono, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 48/00 (2006.01); A61K 47/48 (2006.01); C12N 15/11 (2006.01); A61K 9/51 (2006.01); A61K 41/00 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 47/4823 (2013.01); A61K 9/5161 (2013.01); A61K 41/0047 (2013.01); A61K 48/00 (2013.01); C12N 15/111 (2013.01); C12N 15/113 (2013.01); C12N 2310/14 (2013.01); C12N 2320/32 (2013.01);
Abstract

A complex includes RNA and a positively charged modified polysaccharide selected from starch, amylose, amylopectin, galactan, chitosan, or dextrin. The complex can be formed into a pharmaceutical composition. The complex can be used in methods for RNA transfection, gene therapy and treatment of a disease, disorder or condition. The positively charged modified polysaccharide can be used in connection with RNA transfection into cells.


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