The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 14, 2017

Filed:

Mar. 14, 2014
Applicant:

Osteoceramics, Inc., Ames, IA (US);

Inventor:

Thomas D. McGee, Ames, IA (US);

Assignee:

Osteoceramics, Inc., Ames, IA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); A61K 6/06 (2006.01); A61P 31/00 (2006.01); A61K 31/65 (2006.01); A61K 6/02 (2006.01); A61K 6/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48015 (2013.01); A61K 6/00 (2013.01); A61K 6/0265 (2013.01); A61K 6/06 (2013.01); A61K 6/0631 (2013.01); A61K 31/65 (2013.01); A61K 47/48992 (2013.01);
Abstract

Methods, devices and systems are disclosed for chemically bonding antibiotics to selected substrate materials which are not dissolved in normal physiological processes so that high local concentrations can be achieved during the inflammatory response. The antibiotics will remain permanently bonded to the substrate material until an infection occurs which releases the antibiotic in high concentrations to help control the infection. The high local concentrations may be much higher than systemic toxic levels, and can never reach toxic levels because the local dose is much less than needed to reach systemic toxicity if completely dissolved.


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