The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2017
Filed:
Oct. 20, 2009
Hong-jin Kim, Seoul, KR;
NA Gyong Lee, Seoul, KR;
Yang-je Cho, Seoul, KR;
Jin-wook Jang, Seoul, KR;
Hyoung Jin Kim, Seoul, KR;
Kwang Sung Kim, Hanam-si, KR;
Hong-Jin Kim, Seoul, KR;
Na Gyong Lee, Seoul, KR;
Yang-Je Cho, Seoul, KR;
Jin-Wook Jang, Seoul, KR;
Hyoung Jin Kim, Seoul, KR;
Kwang Sung Kim, Hanam-si, KR;
Eyegene Inc., Seoul, KR;
Abstract
The present invention relates to a pharmaceutical vaccine composition for a human cervical cancer, comprising: (a) (i) a L1 virus-like particle (VLP) of human papillomavirus (HPV) type 16, a L1 VLP of HPV type 18, or a combination thereof; and (ii) a deacylated non-toxic lipooligosaccharide (LOS); and (b) a pharmaceutically acceptable carrier; and a method for preparing a human papillomavirus (HPV) L1 virus-like particle (VLP). The pharmaceutical vaccine composition of the present invention is in both Th1-type immune response (cellular immunity) and Th2-type immune response (humoral immunity) against HPV more excellent than Cervrix™ and Gardasil™, exhibiting a superior efficacy as a vaccine for a human cervical cancer.