The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2017
Filed:
May. 20, 2015
Novartis Ag, Basel, CH;
Jiping Fu, Danville, CA (US);
Subramanian Karur, Dublin, CA (US);
Xiaolin Li, Alameda, CA (US);
Peichao Lu, Pleasant Hill, CA (US);
Wosenu Mergo, Oakland, CA (US);
Alexey Rivkin, Emeryville, CA (US);
Zachary Kevin Sweeney, Redwood City, CA (US);
Meiliana Tjandra, Dublin, CA (US);
Andrew Weiss, San Francisco, CA (US);
Aregahegn Yifru, Pleasant Hill, CA (US);
Novartis AG, Basel, CH;
Abstract
The present invention provides a compound of formula I; or a pharmaceutically acceptable salt thereof, wherein R, R, R, R, R, and A-B are as defined herein, which are non-immunosuppressive, cyclophilin-binding, mPTP blockers and are therefore useful for the prevention or treatment of diseases or disorders such as HCV infection, stroke, multiple sclerosis, HBV infection, HPV infection, asthma, cancer, muscular dystrophy, sepsis, ischemia/reperfusion injury, and heart failure.