The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 14, 2017

Filed:

May. 21, 2013
Applicant:

Insmed Incorporated, Bridgewater, NJ (US);

Inventors:

Walter Perkins, Pennington, NJ (US);

Vladimir Malinin, Plainsboro, NJ (US);

Xingong Li, Robbinsville, NJ (US);

Brian Miller, Hamilton, NJ (US);

Dominique Seidel, München, DE;

Philipp Holzmann, München, DE;

Harald Schulz, Tuttlingen, DE;

Michael Hahn, Krailing, DE;

Assignee:

Insmed Incorporated, Bridgewater, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); A61K 31/7036 (2006.01); A61K 9/00 (2006.01); A61M 11/00 (2006.01); A61M 11/02 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0078 (2013.01); A61K 9/127 (2013.01); A61K 9/1271 (2013.01); A61K 31/7036 (2013.01); A61M 11/005 (2013.01); A61M 11/02 (2013.01);
Abstract

Provided herein are systems for treating a subject with a pulmonary infection, for example, a nontuberculous mycobacterial pulmonary infection, apulmonary infection, a pulmonary infection associated with bronchiectasis, or apulmonary infection. The system includes a pharmaceutical formulation comprising a liposomal aminoglycoside dispersion, and the lipid component of the liposomes consist essentially of electrically neutral lipids. The system also includes a nebulizer which generates an aerosol of the pharmaceutical formulation at a rate greater than about 0.53 gram per minute. The aerosol is delivered to the subject via inhalation for the treatment of the pulmonary infection.


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