The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 07, 2017

Filed:

Dec. 12, 2012
Applicant:

Glaxosmithkline Biologicals SA, Rixensart, BE;

Inventors:

Francesco Berti, Colle Val d'Elsa, IT;

Carl E. Frasch, Martinsburg, WV (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/569 (2006.01); G01N 33/543 (2006.01); C07K 16/12 (2006.01); G01N 33/68 (2006.01); A61K 39/40 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54306 (2013.01); C07K 16/1275 (2013.01); G01N 33/6854 (2013.01); A61K 39/40 (2013.01); A61K 2039/6037 (2013.01); A61K 2039/627 (2013.01); G01N 2400/40 (2013.01);
Abstract

Methods for detecting in a sample the presence of an antibody to a conjugate of an antigen associated with a first carrier by a first association are disclosed. The method comprises contacting a conjugate of the antigen associated with a second carrier by a second association with said sample under conditions that allow binding of the antibody to the antigen; and introducing an agent to detect the presence of the antibody bound to said antigen. The first association and the second association are covalent associations and the first association is different from the second association. Also provided are kits, multiwell plates and conjugates that are useful in the method and further uses of the method. Also provided is a method of releasing a batch of a vaccine comprising a conjugate of an antigen associated with a first carrier by a first association and antibodies useful in this method.


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