The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 07, 2017
Filed:
Jul. 17, 2014
Applicant:
Isis Innovation Limited, Oxford, GB;
Inventors:
Giovanni Maglia, Leuven, BE;
John Hagan Pryce Bayley, Oxford, GB;
Assignee:
OXFORD UNIVERSITY INNOVATION LIMITED, Oxford, GB;
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/487 (2006.01); C07K 14/245 (2006.01); C12Q 1/68 (2006.01); G01N 33/68 (2006.01); G01N 27/447 (2006.01);
U.S. Cl.
CPC ...
G01N 33/48721 (2013.01); C07K 14/245 (2013.01); C12Q 1/6869 (2013.01); G01N 27/447 (2013.01); G01N 33/6872 (2013.01); G01N 2333/705 (2013.01);
Abstract
The invention relates to enhancing translocation of a charged analyte through a transmembrane protein pore. Translocation is enhanced by increasing the net opposing charge of the barrel or channel and/or entrance of the pore. The invention also relates to pores enhanced in accordance with the invention.