The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 07, 2017

Filed:

Feb. 20, 2015
Applicant:

Pharmain Corporation, Bothell, WA (US);

Inventors:

Gerardo M. Castillo, Bothell, WA (US);

Elijah Bolotin, Bothell, WA (US);

Assignee:

PharmaIN Corporation, Bothell, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/00 (2006.01); C07K 17/02 (2006.01); A61K 47/48 (2006.01); A61K 47/42 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 17/02 (2013.01); A61K 47/48038 (2013.01); A61K 47/48315 (2013.01); A61K 38/00 (2013.01); A61K 47/42 (2013.01);
Abstract

The present invention relates to a soluble hydrophobic-core carrier composition comprising (i) a linear polymeric backbone; (ii) a plurality of hydrophilic polymeric protective chains covalently linked and pendant to the polymeric backbone and (iii) at least one hydrophobic moiety covalently linked and pendant to the polymeric backbone. In certain embodiments, the weight ratio of hydrophilic protective chains to hydrophobic moieties in the carrier is at least 15:1. In other embodiments, at least 90% of the residues of the polymeric backbone are coupled to a hydrophilic polymeric protective chain or a hydrophobic moiety. In other embodiments, the composition further comprises (iv) a hydrophobic load molecule dissociably linked to the hydrophobic moiety of the carrier.


Find Patent Forward Citations

Loading…