The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 07, 2017

Filed:

Jul. 24, 2014
Applicants:

Board of Regents, the University of Texas System, Austin, TX (US);

The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD (US);

Inventors:

Constantin G. Ioannides, Houston, TX (US);

George E. Peoples, Fulton, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 7/06 (2006.01); C07K 14/47 (2006.01); A61K 39/17 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/06 (2013.01); A61K 39/0011 (2013.01); C07K 14/47 (2013.01); A61K 38/00 (2013.01); A61K 39/00 (2013.01); A61K 39/17 (2013.01); A61K 2039/54 (2013.01); A61K 2039/545 (2013.01);
Abstract

The present invention is directed to variants of antigens comprising folate binding protein epitopes as a composition associated with providing immunity against a tumor in an individual. The variant is effective in inducing cytotoxic T-lymphocytes but preferably not to the extent that they become sensitive to silencing by elimination, such as by apoptosis, or by anergy, as in unresponsiveness.


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