The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 07, 2017

Filed:

Dec. 18, 2014
Applicant:

Gilead Sciences, Inc., Foster City, CA (US);

Inventors:

Dustin Bringley, San Carlos, CA (US);

Johann Chan, Foster City, CA (US);

Peter Fung, Newport, NY (US);

Katie Keaton, Burlingame, CA (US);

Olga Lapina, Newark, CA (US);

Henry Morrison, Dublin, CA (US);

Dominika Pcion, San Francisco, CA (US);

Assignee:

GILEAD SCIENCES, INC., Foster City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4985 (2006.01); C07D 498/16 (2006.01); A61K 45/06 (2006.01); C07K 5/083 (2006.01);
U.S. Cl.
CPC ...
C07D 498/16 (2013.01); A61K 31/4985 (2013.01); A61K 45/06 (2013.01); C07K 5/0808 (2013.01);
Abstract

Crystalline forms of the anti-HCV compound (1aR,5S,8S,9S,10R,22aR)-5-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclopropyl]-9-ethyl-18,18-difluoro-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxamide (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the crystalline forms.


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