The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 07, 2017

Filed:

Jun. 16, 2010
Applicants:

David S. Garvey, Dover, MA (US);

Gregory J. Larosa, Newton, MA (US);

Jeremy R. Greenwood, Brooklyn, NY (US);

Mark L. Brewer, Portland, OR (US);

Tan Quach, Scarborough, CA;

Jamie B. Côté, Newmarket, CA;

Judd Berman, Toronto, CA;

Inventors:

David S. Garvey, Dover, MA (US);

Gregory J. LaRosa, Newton, MA (US);

Jeremy R. Greenwood, Brooklyn, NY (US);

Mark L. Brewer, Portland, OR (US);

Tan Quach, Scarborough, CA;

Jamie B. Côté, Newmarket, CA;

Judd Berman, Toronto, CA;

Assignee:

BIKAM PHARMACEUTICALS, INC., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 279/00 (2006.01); C07D 295/00 (2006.01); C07D 243/08 (2006.01); C07D 207/12 (2006.01); C07D 207/14 (2006.01); C07D 295/182 (2006.01); C07D 295/185 (2006.01); C07D 295/194 (2006.01); C07D 491/10 (2006.01); C07D 493/08 (2006.01);
U.S. Cl.
CPC ...
C07D 243/08 (2013.01); C07D 207/12 (2013.01); C07D 207/14 (2013.01); C07D 295/182 (2013.01); C07D 295/185 (2013.01); C07D 295/194 (2013.01); C07D 491/10 (2013.01); C07D 493/08 (2013.01);
Abstract

Compounds and compositions of said compounds along with methods of use of compounds are disclosed for treating ophthalmic conditions related to mislocalization of opsin proteins, the misfolding of mutant opsin proteins and the production of toxic visual cycle products that accumulate in the eye. Compounds and compositions useful in the these methods, either alone or in combination with other therapeutic agents, are also described.


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