The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 07, 2017
Filed:
Apr. 02, 2012
Hiroyuki Saito, Kashiwa, JP;
Katsutoshi Kobayashi, Kashiwa, JP;
Ryosuke Tanaka, Kashiwa, JP;
Mitsunori Harada, Kashiwa, JP;
Yasuki Kato, Kashiwa, JP;
Hiroyuki Saito, Kashiwa, JP;
Katsutoshi Kobayashi, Kashiwa, JP;
Ryosuke Tanaka, Kashiwa, JP;
Mitsunori Harada, Kashiwa, JP;
Yasuki Kato, Kashiwa, JP;
NANOCARRIER CO., LTD., Kashiwa-shi, JP;
Abstract
A pharmaceutical composition includes a block copolymer having a hydrophilic segment, a hydrophobic segment, and a boronic acid compound bound to a side chain of the hydrophobic segment via a linker moiety that includes a heterocyclic structure. The heterocyclic structure contains a cyclic skeleton that includes a boron atom of the boronic acid compound, one or two atom(s) X bound to the boron atom and selected from an oxygen atom and a nitrogen atom, and one or two carbon atom(s) (respectively) bound to the atom(s) X. The block copolymer further includes at least one organic group bound to the carbon atom(s). The organic group(s) contain(s) an aromatic group or cyclic alkyl group that sterically protects a boronic acid ester bond and/or a boron amide bond resulting from bonding between the boron atom and the atom(s) X.