The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 07, 2017
Filed:
Oct. 08, 2015
Applicant:
Zafgen, Inc., Boston, MA (US);
Inventors:
Susan Mary Cramp, Harlow, GB;
Hazel Joan Dyke, Harlow, GB;
Thomas David Pallin, Harlow, GB;
Robert Zahler, Pennington, NJ (US);
Assignee:
Zafgen, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 317/14 (2006.01); A61K 31/5383 (2006.01); A61K 9/00 (2006.01); A61K 31/407 (2006.01); A61K 31/4745 (2006.01); A61K 31/4188 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5383 (2013.01); A61K 9/0053 (2013.01); A61K 31/407 (2013.01); A61K 31/4188 (2013.01); A61K 31/4745 (2013.01);
Abstract
The invention provides tricyclic sulfonamide compounds and their use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of making various tricyclic compounds are provided. The compounds are contemplated to have activity against methionyl aminopeptidase 2. For example, the invention relates in part to tricyclic sulfonamide compounds represented by Formula I: or pharmaceutically acceptable salts or stereoisomers thereof, wherein A, B, D, R, R, Y, X and n are as defined herein.