The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 07, 2017

Filed:

Sep. 05, 2012
Applicants:

Stephen G. Carter, Andover, MA (US);

Zhen Zhu, Andover, MA (US);

Kanu Patel, Londonderry, NH (US);

Diane Kozwich, Nottingham, NH (US);

Inventors:

Stephen G. Carter, Andover, MA (US);

Zhen Zhu, Andover, MA (US);

Kanu Patel, Londonderry, NH (US);

Diane Kozwich, Nottingham, NH (US);

Assignee:

BioChemics, Inc., Danvers, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/192 (2006.01); A61K 47/32 (2006.01); A61P 29/00 (2006.01); A61K 9/00 (2006.01); A61K 9/70 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0014 (2013.01); A61K 9/7023 (2013.01); A61K 47/32 (2013.01);
Abstract

Set forth herein is a preparation of ibuprofen (2-(4-isobutylphenyl) propionic acid) in the free acid form that is suitable for topical administration. The topical ibuprofen formulation is prepared by dissolving the free acid form of ibuprofen, or preparing a homogeneous suspension of the free acid form of ibuprofen, in the presence of a pharmaceutically acceptable solvent so as to produce a topical drug formulation compatible with the penetration of 2-(4-isobutylphenyl) propionic acid through the skin tissue. Topical formulations of ibuprofen can be based on a pharmaceutically acceptable solvent such as, e.g., a pyrrolidone solvent or dimethylacetamide.


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