The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 07, 2017

Filed:

Apr. 13, 2012
Applicants:

Karsten Heyne, Grossbeeren, DE;

Martin Stockmann, Berlin, DE;

Tom Rubin, Berlin, DE;

Inventors:

Karsten Heyne, Grossbeeren, DE;

Martin Stockmann, Berlin, DE;

Tom Rubin, Berlin, DE;

Assignee:

HUMEDICS GMBH, Berlin, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/08 (2006.01); A61B 5/083 (2006.01); A61B 5/097 (2006.01); A61B 5/087 (2006.01); A61B 5/00 (2006.01); G01J 3/42 (2006.01); G01R 33/465 (2006.01); G01T 1/29 (2006.01); H01J 49/26 (2006.01);
U.S. Cl.
CPC ...
A61B 5/0836 (2013.01); A61B 5/087 (2013.01); A61B 5/0813 (2013.01); A61B 5/097 (2013.01); A61B 5/72 (2013.01); G01J 3/42 (2013.01); G01R 33/465 (2013.01); G01T 1/2985 (2013.01); H01J 49/26 (2013.01);
Abstract

A method for determining the metabolic capacity of an enzyme includes time-resolved determination of the concentration of a product in exhaled air. The product is created by metabolism of a substrate, previously administered to an individual, by an enzyme of the individual. The product concentration is determined until the maximum product concentration in the exhaled air is reached. A model function is fitted to measured values of the product concentration, obtained by the time-resolved determination of the product concentration between start and end times. The metabolic capacity of the enzyme is determined based on parameters of the model function. Determining the metabolic capacity of the enzyme takes place based on at least two parameters of the model function, wherein the maximum value and time constant of the model function are not selected as parameters at the same time, and the start and/or end times are not selected as parameters.


Find Patent Forward Citations

Loading…