The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2017

Filed:

Oct. 22, 2010
Applicants:

Gualberto Ruano, Milford, CT (US);

David Victor Villagra, West Hartford, CT (US);

Mohan Ranjit Kumar Kocherla, Hartford, CT (US);

Andreas Windemuth, South Glastonbury, CT (US);

John W. Goethe, Avon, CT (US);

Inventors:

Gualberto Ruano, Milford, CT (US);

David Victor Villagra, West Hartford, CT (US);

Mohan Ranjit Kumar Kocherla, Hartford, CT (US);

Andreas Windemuth, South Glastonbury, CT (US);

John W. Goethe, Avon, CT (US);

Assignee:

GENOMAS, INC., Hartford, CT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); G06F 19/18 (2011.01); C12Q 1/68 (2006.01); G06F 19/00 (2011.01);
U.S. Cl.
CPC ...
G06F 19/18 (2013.01); G06F 19/3431 (2013.01);
Abstract

Disclosed herein are compositions and methods relevant to a novel Drug Metabolism Reserve Physiotype to determine the metabolic capacity of a human individual. The Drug Metabolism Reserve Physiotype allows the determination of the innate metabolic capacity of the patient relevant to antidepressant and stimulant treatment and can be predicted and diagnosed simply from a blood sample. In the disclosed method, an individual is genotyped for a plurality of polymorphisms in a gene encoding CYP2C9, a gene encoding CYP2C19 and a gene encoding CYP2D6, and the genotypes are used to produce four novel indices, which relate to the metabolic capacity of the human individual.


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