The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2017
Filed:
Mar. 02, 2015
Aviva Biosciences Corporation, San Diego, CA (US);
Ping Lin, San Diego, CA (US);
Douglas T. Yamanishi, Huntington Beach, CA (US);
George Walker, San Diego, CA (US);
Junquan Xu, San Diego, CA (US);
Mingxian Huang, San Diego, CA (US);
Guoliang Tao, San Diego, CA (US);
Lei Wu, San Diego, CA (US);
Xiaobo Wang, San Diego, CA (US);
Joe Ouyang, San Diego, CA (US);
Jing Cheng, Beijing, CN;
Jia Xu, Washington, DC (US);
AVIVA BIOSCIENCES CORPORATION, San Diego, CA (US);
Abstract
The present invention recognizes that diagnosis and prognosis of many conditions can depend on the enrichment of rare cells, especially tumor cells, from a complex fluid sample such as a blood sample. In particular, the present invention is directed to methods and compositions for detecting a non-hematopoietic cell, e.g., a non-hematopoietic tumor cell, in a blood sample via, inter alia, removing red blood cells (RBCs) from a blood sample using a non-centrifugation procedure, removing white blood cells (WBCs) from said blood sample to enrich a non-hematopoietic cell, if any, from said blood sample; and assessing the presence, absence and/or amount of said enriched non-hematopoietic cell.