The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2017

Filed:

Mar. 15, 2013
Applicants:

Vib Vzw, Ghent, BE;

Vrije Universiteit Brussel, Brussels, BE;

Inventors:

Jo Van Ginderachter, Ninove, BE;

Patrick De Baetselier, Berchem, BE;

Nick Devoogdt, Zemst, BE;

Tony Lahoutte, Ganshoren, BE;

Damya Laoui, Limal, BE;

Kiavash Movahedi, Frankfurt am Main, DE;

Geert Raes, Sint-Genesius-Rode, BE;

Steve Schoonooghe, Kessel-Lo, BE;

Assignees:

VIB VZW, Ghent, BE;

Vrije Universiteit Brussel, Brussels, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 51/10 (2006.01); A61K 47/48 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
C07K 16/2851 (2013.01); A61K 47/48484 (2013.01); A61K 47/48561 (2013.01); A61K 47/48761 (2013.01); A61K 51/1027 (2013.01); A61K 51/1096 (2013.01); B82Y 5/00 (2013.01); C07K 2317/22 (2013.01); C07K 2317/35 (2013.01); C07K 2317/569 (2013.01);
Abstract

The disclosure relates to immunoglobulin single variable domains directed against human macrophage mannose receptor (MMR) and their uses in the field of oncology. More specifically, it concerns immunoglobulin single variable domains, including single-domain antibodies (sdAbs), against human MMR and their use in targeting and in vivo imaging of tumor-associated macrophages, with applications in the field of cancer diagnostics and therapeutics and monitoring of the disease.


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