The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2017

Filed:

Apr. 02, 2015
Applicants:

Baxter International Inc., Deerfield, IL (US);

Baxter Healthcare SA, Glattpark (Opfikon), CH;

Inventors:

Michael Dockal, Vienna, AT;

Rudolf Hartmann, Bisamberg, AT;

Markus Fries, Vienna, AT;

Friedrich Scheiflinger, Vienna, AT;

Hartmut Ehrlich, Vienna, AT;

Ulrich Reineke, Berlin, DE;

Frank Osterkamp, Berlin, DE;

Thomas Polakowski, Berlin, DE;

Assignees:

BAXALTA GMBH, , CH;

BAXALTA INCORPORATED, Bannockburn, IL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/57 (2006.01); C07K 14/745 (2006.01); C07K 7/08 (2006.01); C07K 14/81 (2006.01); G01N 33/68 (2006.01); G06F 19/16 (2011.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); C07K 14/8114 (2013.01); G01N 33/68 (2013.01); G06F 19/16 (2013.01); A61K 38/00 (2013.01); G01N 2333/8114 (2013.01); G01N 2333/96444 (2013.01); G01N 2333/96447 (2013.01); G01N 2500/02 (2013.01); G01N 2500/20 (2013.01);
Abstract

The invention provides peptides that bind Tissue Factor Pathway Inhibitor (TFPI), including TFPI-inhibitory peptides, and compositions thereof. The peptides may be used to inhibit a TFPI, enhance thrombin formation in a clotting factor-deficient subject, increase blood clot formation in a subject, treat a blood coagulation disorder in a subject, purify TFPI, and identify a TFPI-binding compound.


Find Patent Forward Citations

Loading…