The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2017

Filed:

Jun. 14, 2013
Applicant:

Reata Pharmaceuticals, Inc., Irving, TX (US);

Inventors:

Eric Anderson, Southlake, TX (US);

Christopher F. Bender, Garland, TX (US);

Xin Jiang, Coppell, TX (US);

Xiaofeng Liu, Coppell, TX (US);

Haizhou Sun, Irving, TX (US);

Melean Visnick, Irving, TX (US);

Assignee:

REATA PHARMACEUTICALS, INC., Irving, TX (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07J 71/00 (2006.01); C07J 75/00 (2006.01); C07D 493/22 (2006.01); A61K 31/336 (2006.01); C07J 63/00 (2006.01);
U.S. Cl.
CPC ...
C07J 71/001 (2013.01); C07J 63/008 (2013.01); A61K 31/336 (2013.01); C07D 493/22 (2013.01); C07J 75/00 (2013.01);
Abstract

Disclosed herein are novel A-ring epoxidized triterpenoid compounds and derivatives thereof, including those of the formula (I), wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits, and articles of manufacture comprising such compounds. Methods and intermediates useful for making the compounds, and methods of using the compounds, for example as antioxidant inflammation modulators, and compositions thereof are also provided.


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