The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2017
Filed:
Oct. 03, 2014
Universitaet Basel, Petersgraben, CH;
Piqur Therapeutics Ag, Basel, CH;
Vladimir Cmiljanovic, Basel, CH;
Paul Hebeisen, Basel, CH;
Eileen Jackson, Basel, CH;
Florent Beaufils, Bartenheim, FR;
Thomas Bohnacker, Basel, CH;
Matthias Wymann, Bern, CH;
PIQUR THERAPEUTICS AG, Basel, CH;
UNIVERSITAET BASEL, Basel, CH;
Abstract
The invention relates to novel phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) inhibitor compounds of formula (I) and (II), which are conformationally restricted, and for which the meaning of the substituents are listed in the description. Preferred compounds are those wherein X isoxygen, Ris morpholino and Ris substituted phenyl or heteroaryl. These compounds are useful, either alone or in combination with further therapeutic agents, for treating disorders mediated by lipid kinases.