The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2017

Filed:

May. 31, 2011
Applicants:

Peng LI, New York, NY (US);

Hailin Zheng, New York, NY (US);

Jun Zhao, New York, NY (US);

Lawrence P. Wennogle, New York, NY (US);

Inventors:

Peng Li, New York, NY (US);

Hailin Zheng, New York, NY (US);

Jun Zhao, New York, NY (US);

Lawrence P. Wennogle, New York, NY (US);

Assignee:

INTRA-CELLULAR THERAPIES, INC., New York, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/165 (2006.01); A61K 31/573 (2006.01); A61K 31/565 (2006.01); A61K 31/557 (2006.01); A61K 31/519 (2006.01); A61K 31/19 (2006.01); C07D 487/04 (2006.01); C07D 487/14 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 487/14 (2013.01); A61K 31/165 (2013.01); A61K 31/19 (2013.01); A61K 31/519 (2013.01); A61K 31/557 (2013.01); A61K 31/565 (2013.01); A61K 31/573 (2013.01); A61K 45/06 (2013.01); C07D 487/04 (2013.01);
Abstract

The present invention relates to optionally substituted 4,5,7,8-tetrahydro-(optionally 4-oxo, 4-thioxo or 4-imino)-(1H or 2H)-imidazo[1,2-a]pyrazolo[4,3-e]pyrimidine or 4,5,7,8,9-pentahydro-(optionally 4-oxo, 4-thioxo or 4-imino)-(1H or 2H)-pyrimido[1,2-a]pyrazolo[4,3-e]pyrimidine compounds, and methods of using said compound, e.g., wherein the treatment relates to diseases involving disorders of the dopamine D1 receptor intracellular pathway, such as, among others, Parkinson's disease, depression, narcolepsy, damage to cognitive function, e.g., in schizophrenia.


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