The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2017

Filed:

Aug. 28, 2014
Applicant:

University of Utah, Salt Lake City, UT (US);

Inventors:

Hariprasad Vankayalapati, Draper, UT (US);

Sunil Sharma, Salt Lake City, UT (US);

Venkataswamy Sorna, Salt Lake City, UT (US);

Assignee:

University of Utah Research Foundation, Salt Lake City, UT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 401/12 (2006.01); C07D 235/32 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 235/32 (2013.01); C07D 401/12 (2013.01);
Abstract

The present invention provides compounds which are useful as inhibitors of lysine-specific demethylase 1 ('LSD1'). The present invention also relates to pharmaceutical compositions containing these compounds. The present invention also relates to a method for preparing these compounds. The present invention also relates to a method of treating a mammalian disorder in which LSD1 levels are elevated by administering these compounds and compositions to a patient in need thereof. The present invention also relates to a method for decreasing histone demethylase activity in a mammal comprising administering to the mammal an effective amount of these compounds and compositions.


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