The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2017
Filed:
Aug. 21, 2015
Applicant:
Janssen Pharmaceutica, N.v., Beerse, BE;
Inventors:
Kristof Van Emelen, Sint-Niklaas, BE;
Marc Gustaaf Celine Verdonck, Gierle, BE;
Sven Franciscus Anna Van Brandt, Nijlen, BE;
Patrick Rene Angibaud, Fontaine-Bellenger, FR;
Lieven Meerpoel, Beerse, BE;
Alexey Borisovich Dyatkin, Maple Glen, PA (US);
Assignee:
Janssen Pharmaceutica NV, Beerse, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 217/04 (2006.01); A61K 31/472 (2006.01); C07D 413/12 (2006.01); C07D 211/14 (2006.01); A61K 31/402 (2006.01); C07D 409/14 (2006.01); C07D 207/09 (2006.01); C07D 207/14 (2006.01); C07D 211/58 (2006.01); C07D 213/78 (2006.01); C07D 217/02 (2006.01); C07D 239/42 (2006.01); C07D 295/155 (2006.01); C07D 295/26 (2006.01); C07D 307/68 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); C07D 403/04 (2006.01); C07D 409/12 (2006.01); C07D 413/04 (2006.01); C07D 471/04 (2006.01); C07D 471/10 (2006.01); C07D 513/04 (2006.01); C12Q 1/48 (2006.01); A61K 31/435 (2006.01); A61K 31/495 (2006.01); A61K 31/506 (2006.01); A61K 45/06 (2006.01); A61K 31/4427 (2006.01); A61K 31/454 (2006.01); A61K 31/5377 (2006.01); A61K 31/55 (2006.01); A61K 31/40 (2006.01); A61K 31/496 (2006.01); C07D 217/16 (2006.01); C07D 405/06 (2006.01); A61K 31/4545 (2006.01); C07D 403/12 (2006.01); C12Q 1/34 (2006.01);
U.S. Cl.
CPC ...
C07D 413/12 (2013.01); A61K 31/40 (2013.01); A61K 31/402 (2013.01); A61K 31/435 (2013.01); A61K 31/4427 (2013.01); A61K 31/454 (2013.01); A61K 31/4545 (2013.01); A61K 31/472 (2013.01); A61K 31/495 (2013.01); A61K 31/496 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 31/55 (2013.01); A61K 45/06 (2013.01); C07D 207/09 (2013.01); C07D 207/14 (2013.01); C07D 211/14 (2013.01); C07D 211/58 (2013.01); C07D 213/78 (2013.01); C07D 217/02 (2013.01); C07D 217/04 (2013.01); C07D 217/16 (2013.01); C07D 239/42 (2013.01); C07D 295/155 (2013.01); C07D 295/26 (2013.01); C07D 307/68 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 403/04 (2013.01); C07D 403/12 (2013.01); C07D 405/06 (2013.01); C07D 409/12 (2013.01); C07D 409/14 (2013.01); C07D 413/04 (2013.01); C07D 471/04 (2013.01); C07D 471/10 (2013.01); C07D 513/04 (2013.01); C12Q 1/34 (2013.01); C12Q 1/48 (2013.01);
Abstract
This invention comprises the novel compounds of formula (I) wherein n, R, R, R, R, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.