The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2017
Filed:
Apr. 29, 2015
The South Dakota Board of Regents, Pierre, SD (US);
Sanford Research, Sioux Falls, SD (US);
Xiangming Guan, Brookings, SD (US);
Chandrahar Dwivedi, Brookings, SD (US);
Yinghong Li, Beijing, CN;
Yang Yang, Brookings, SD (US);
John H. Lee, Sioux Falls, SD (US);
Wilson Keith Miskimins, Alcester, SD (US);
The South Dakota Board of Regents, Pierre, SD (US);
Sanford Research, Sioux Falls, SD (US);
Abstract
The invention novel compounds, pharmaceutical compositions and methods useful for preventing or treating cancer in animals and humans. Also, the invention provides novel prodrugs useful for reducing tumor size, and inhibiting the growth of cancers, inhibiting tumor cell growth and tumor cell proliferation, and promoting apoptosis of tumor cells. When used in combination with chemoradiation therapy, the novel compounds, compositions and prodrugs provided herein can improve the effectiveness of chemoradiation therapy. The novel compounds, compositions and prodrugs of the invention inhibit PDK and LDH in unique and effective ways.