The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2017
Filed:
Jul. 10, 2015
Applicant:
Mallinckrodt Llc, Hazelwood, MO (US);
Inventors:
Subo Liao, Hazelwood, MO (US);
Joseph McClurg, Hazelwood, MO (US);
Bobby Trawick, Hazelwood, MO (US);
Assignee:
Mallinckrodt LLC, Hazelwood, MO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 213/02 (2006.01); C07C 213/08 (2006.01); C07C 45/62 (2006.01); C07C 45/68 (2006.01); C07C 45/69 (2006.01); C07C 45/65 (2006.01);
U.S. Cl.
CPC ...
C07C 213/08 (2013.01); C07C 45/62 (2013.01); C07C 45/65 (2013.01); C07C 45/68 (2013.01); C07C 45/69 (2013.01); C07C 213/02 (2013.01); C07B 2200/07 (2013.01);
Abstract
The invention provides methods for preparing substituted phenylalkanes. In particular, the processes comprise reacting a phenyl boronic compound with an α-β unsaturated carbonyl-containing compound via an asymmetric 1,4-addition reaction. The processes may be useful in the synthesis of tapentadol.