The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2017

Filed:

Sep. 30, 2014
Applicant:

Gnubio, Inc., Cambridge, MA (US);

Inventors:

Sepehr Kiani, Cambridge, MA (US);

Tony Hung, Cambridge, MA (US);

Peter Stokes, Cambridge, MA (US);

Julia Sharpe, Cambridge, MA (US);

Assignee:

GnuBio, Inc., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); F16K 99/00 (2006.01); G01N 1/18 (2006.01); C12M 1/34 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502738 (2013.01); B01L 3/50273 (2013.01); B01L 3/502784 (2013.01); B01L 2200/0621 (2013.01); B01L 2200/0684 (2013.01); B01L 2200/10 (2013.01); B01L 2200/16 (2013.01); B01L 2300/0672 (2013.01); B01L 2300/087 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/0887 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/0638 (2013.01); B01L 2400/0655 (2013.01); B01L 2400/0683 (2013.01); B01L 2400/0688 (2013.01); F16K 99/00 (2013.01);
Abstract

Methods and systems for controlling fluid flow through a cartridge for use in an assay of a fluid sample for detection of a target analyte. In one aspect, the cartridge includes a microfluidic device having a network of microfluidic channels, one or more reservoirs and one or more actuatable valves for controlling fluid flow from the reservoirs through the microfluidic channels. In some embodiments, the valve includes a deformable membrane movable between a closed configuration in which the membrane seals against the microfluidic device inhibiting fluid flow and an open configuration moved away from the microfluidic device to allow fluid flow through the microfluidic channels. Other valve embodiments utilize frangible membranes or user-removable membrane.


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