The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2017
Filed:
Feb. 07, 2012
Axel Hoffmann, Wehrheim, DE;
Heinrich Lannert, Schwetzingen, DE;
Klaus Brischwein, Munich, DE;
Frederic Christian Pipp, Gruendau, DE;
Juergen Reindl, Rossdorf, DE;
Karin Groll, Muehltal, DE;
Michael Zuehlsdorf, Darmstadt, DE;
Otmar Pfaff, Frankfurt am Main, DE;
Sabine Raab, Rosbach, DE;
Ulrike Dau, Darmstadt, DE;
Benoit Destenaves, Peron, FR;
Axel Hoffmann, Wehrheim, DE;
Heinrich Lannert, Schwetzingen, DE;
Klaus Brischwein, Munich, DE;
Frederic Christian Pipp, Gruendau, DE;
Juergen Reindl, Rossdorf, DE;
Karin Groll, Muehltal, DE;
Michael Zuehlsdorf, Darmstadt, DE;
Otmar Pfaff, Frankfurt am Main, DE;
Sabine Raab, Rosbach, DE;
Ulrike Dau, Darmstadt, DE;
Benoit Destenaves, Peron, FR;
Merck Patent GmbH, Darmstadt, DE;
Abstract
The invention is directed to the treatment of prostate cancer by means of antibodies. Above all, the invention relates to the administration of an anti-alpha-v integrin (receptor) antibody to patients suffering from prostate cancer, especially castration-resistant prostate cancer (CRPC), optionally accompanied by lymph node and bone tissue metastases (mCRPC). In particular, the invention relates to the therapy of said patients by means of the anti-angiogenic antibody DI17E6 and structural mutants thereof.