The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2017

Filed:

Jul. 30, 2014
Applicants:

Konkuk University Industrial Cooperation Corp., Seoul, KR;

KR Biotech Co., Ltd., Seoul, KR;

Inventors:

Young-Bong Kim, Goyang-Si, KR;

Hee Jung Lee, Seoul, KR;

Nuri Park, Seoul, KR;

Yu-Kyoung Oh, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/866 (2006.01); A61K 39/12 (2006.01); C12N 15/86 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); A61K 2039/5256 (2013.01); C12N 2710/14143 (2013.01); C12N 2710/14145 (2013.01); C12N 2710/14171 (2013.01); C12N 2710/20034 (2013.01); C12N 2740/10022 (2013.01); C12N 2800/22 (2013.01); C12N 2810/6054 (2013.01); C12N 2830/60 (2013.01); C12N 2830/85 (2013.01);
Abstract

The present invention relates to a recombinant baculovirus comprising: (a) a nucleotide sequence encoding a foreign virus envelope protein; (b) a first promoter operatively linked to the envelope-encoding nucleotide sequence; (c) a nucleotide sequence encoding an antigen protein; and (d) a second promoter operatively linked to the antigen-encoding nucleotide sequence; and a vaccine composition using the same. The recombinant baculovirus of the present invention has an excellent efficacy on both humoral and cellular immune responses against a specific antigen (e.g., HPV L1), enabling to function as a more efficient DNA vaccine.


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