The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2017
Filed:
Dec. 13, 2012
Applicant:
Henry Ford Health System, Detroit, MI (US);
Inventors:
Mark E. Katakowski, Ann Arbor, MI (US);
Benjamin A. L. Buller, Detroit, MI (US);
Michael Chopp, Southfield, MI (US);
Assignee:
Henry Ford Health System, Detroit, MI (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 35/28 (2015.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01); A61K 9/127 (2006.01);
U.S. Cl.
CPC ...
A61K 35/28 (2013.01); A61K 9/127 (2013.01); C12N 15/111 (2013.01); C12N 15/113 (2013.01); C12N 2310/141 (2013.01); C12N 2320/32 (2013.01); C12N 2330/50 (2013.01);
Abstract
Some embodiments comprise methods, systems, and compositions to produce and/or administer modified exosomes or other vesicles containing one or more selected microRNAs, including but not limited to, miR-146b. Some embodiments also comprise the therapeutic administration and use of such modified exosomes and/or producer cells to treat mammalian injuries and diseases, including in human beings.