The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2017

Filed:

Aug. 18, 2014
Applicant:

Flexion Therapeutics, Inc., Burlington, MA (US);

Inventors:

Neil Bodick, Boston, MA (US);

Robert C. Blanks, Auburndale, MA (US);

Anjali Kumar, Belmont, MA (US);

Michael D. Clayman, Gloucester, MA (US);

Mark Moran, Orinda, CA (US);

Assignee:

FLEXION THERAPEUTICS, INC., Burlington, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 9/50 (2006.01); A61K 31/573 (2006.01); A61K 9/16 (2006.01); A61K 31/58 (2006.01); A61K 9/00 (2006.01); A61K 47/34 (2006.01);
U.S. Cl.
CPC ...
A61K 31/58 (2013.01); A61K 9/0019 (2013.01); A61K 9/0024 (2013.01); A61K 9/14 (2013.01); A61K 9/1641 (2013.01); A61K 9/1647 (2013.01); A61K 9/1694 (2013.01); A61K 31/573 (2013.01); A61K 47/34 (2013.01);
Abstract

Corticosteroid microparticle formulations are provided for use for treating pain, including pain caused by inflammatory diseases such as osteoarthritis or rheumatoid arthritis, and for slowing, arresting or reversing structural damage to tissues caused by an inflammatory disease, for example damage to articular and/or peri-articular tissues caused by osteoarthritis or rheumatoid arthritis. Corticosteroid microparticle formulations are administered locally as a sustained release dosage form (with or without an immediate release component) that results in efficacy accompanied by clinically insignificant or no measurable effect on endogenous cortisol production.


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