The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2017
Filed:
Dec. 11, 2014
Applicant:
Hikma Pharmaceuticals, Amman, JO;
Inventor:
Murray Ducharme, St. Laurent, CA;
Assignee:
HIKMA PHARMACEUTICALS LLC, , JO;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); A61K 31/12 (2006.01); A61K 31/165 (2006.01); A61K 31/4164 (2006.01); A61K 31/4196 (2006.01); A61K 31/138 (2006.01); A61K 31/133 (2006.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); A61K 31/12 (2013.01); A61K 31/133 (2013.01); A61K 31/138 (2013.01); A61K 31/165 (2013.01); A61K 31/4164 (2013.01); A61K 31/4196 (2013.01);
Abstract
The invention provides improved methods for coadministration of colchicine with drugs metabolized by CYP3A4 (anciently referred to as cytochrome P450 isozyme 3A4) or the P-glycoprotein transporter, but not both. The method enables non-toxic coadministration of colchicine and the second drug at their ordinary levels safely and effectively without reducing the dose or frequency for either drug.