The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2017

Filed:

Jun. 14, 2011
Applicants:

Volker Schulze, OT Bergfelde, DE;

Dirk Kosemund, Berlin, DE;

Hartmut Schirok, Langenfeld, DE;

Benjamin Bader, Berlin, DE;

Philip Lienau, Berlin, DE;

Antje Margret Wengner, Berlin, DE;

Hans Briem, Berlin, DE;

Simon Holton, Berlin, DE;

Gerhard Siemeister, Berlin, DE;

Stefan Prechtl, Berlin, DE;

Marcus Koppitz, Berlin, DE;

Detlef Stöckigt, Potsdam, DE;

Olaf Prien, Berlin, DE;

Inventors:

Volker Schulze, OT Bergfelde, DE;

Dirk Kosemund, Berlin, DE;

Hartmut Schirok, Langenfeld, DE;

Benjamin Bader, Berlin, DE;

Philip Lienau, Berlin, DE;

Antje Margret Wengner, Berlin, DE;

Hans Briem, Berlin, DE;

Simon Holton, Berlin, DE;

Gerhard Siemeister, Berlin, DE;

Stefan Prechtl, Berlin, DE;

Marcus Koppitz, Berlin, DE;

Detlef Stöckigt, Potsdam, DE;

Olaf Prien, Berlin, DE;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 513/02 (2006.01); C07D 515/02 (2006.01); C07D 249/08 (2006.01); A61K 31/44 (2006.01); A61K 31/437 (2006.01); A61K 45/06 (2006.01); C07D 471/04 (2006.01); C07D 519/00 (2006.01); A61K 31/167 (2006.01); A61K 31/277 (2006.01); A61K 31/282 (2006.01); A61K 31/337 (2006.01); A61K 31/427 (2006.01); A61K 31/428 (2006.01); A61K 31/444 (2006.01); A61K 31/4545 (2006.01); A61K 31/496 (2006.01); A61K 31/513 (2006.01); A61K 31/5377 (2006.01); A61K 31/541 (2006.01); A61K 31/565 (2006.01); A61K 31/675 (2006.01); A61K 31/69 (2006.01); A61K 31/704 (2006.01); A61K 31/7048 (2006.01); A61K 33/24 (2006.01); A61K 38/14 (2006.01); A61K 39/395 (2006.01); C07D 491/08 (2006.01); C07D 491/107 (2006.01);
U.S. Cl.
CPC ...
A61K 31/437 (2013.01); A61K 31/167 (2013.01); A61K 31/277 (2013.01); A61K 31/282 (2013.01); A61K 31/337 (2013.01); A61K 31/427 (2013.01); A61K 31/428 (2013.01); A61K 31/444 (2013.01); A61K 31/4545 (2013.01); A61K 31/496 (2013.01); A61K 31/513 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); A61K 31/565 (2013.01); A61K 31/675 (2013.01); A61K 31/69 (2013.01); A61K 31/704 (2013.01); A61K 31/7048 (2013.01); A61K 33/24 (2013.01); A61K 38/14 (2013.01); A61K 39/395 (2013.01); A61K 45/06 (2013.01); C07D 471/04 (2013.01); C07D 491/08 (2013.01); C07D 491/107 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention relates to substituted triazolopyridine compounds of general formula (I): in which R, R, R, R, and Rare as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease of uncontrolled cell growth, proliferation and/or survival as well as to the use of intermediate compounds for the preparation of said compounds.


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